| Description |
Smart name |
Pfam name |
Pfam ID |
| Amyloid A4 | A4_EXTRA | A4_EXTRA | PF02177 |
| Plant lipid transfer protein / seed storage protein / trypsin-alpha amylase inhibitor domain family | AAI | Tryp_alpha_amyl | PF00234 |
| Serum albumin | ALBUMIN | Serum_albumin | PF00273 |
| Ami_2 | Ami_2 | Amidase_2 | PF01510 |
| Ami_3 | Ami_3 | Amidase_3 | PF01520 |
| Adhesion-associated domain present in MUC4 and other proteins | AMOP | AMOP | PF01821 |
| APPLE domain | APPLE | PAN | PF00024 |
| Bulb-type mannose-specific lectin | B_lectin | B_lectin | PF01453 |
| Bacterial Ig-like domain (group 1) | BID_1 | Big_1 | PF02369 |
| Bacterial Ig-like domain 2 | BID_2 | Big_2 | PF02368 |
| Bacterial OsmY and nodulation domain | BON | BON | PF04972 |
| Bowman-Birk type proteinase inhibitor | BowB | Bowman-Birk_leg | PF00228 |
| BPI/LBP/CETP N-terminal domain | BPI1 | LBP_BPI_CETP | PF01273 |
| Complement component C1q domain | C1Q | C1q | PF00386 |
| Netrin C-terminal Domain | C345C | NTR | PF01759 |
| C-terminal tandem repeated domain in type 4 procollagens | C4 | C4 | PF01413 |
| Cadherin repeats | CA | Cadherin | PF00028 |
| Calcitonin | CALCITONIN | Calc_CGRP_IAPP | PF00214 |
| Cellulose Binding Domain Type IV | CBD_IV | CBM_6 | PF03422 |
| Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR) | CCP | Sushi | PF00084 |
| CFEM | CFEM | CFEM | PF05730 |
| A domain in the BMP inhibitor chordin and in microbial proteins | CHRD | CHRD | PF07452 |
| Chitin binding domain | ChtBD1 | Chitin_bind_1 | PF00187 |
| Chitin-binding domain type 2 | ChtBD2 | CBM_14 | PF01607 |
| Chitin-binding domain type 3 | ChtBD3 | CBM_5_12 | PF02839 |
| Clostridial hydrophobic, with a conserved W residue, domain | ChW | ChW | PF01584 |
| CLUSTERIN alpha chain | CLa | Clusterin | PF01093 |
| CLUSTERIN Beta chain | CLb | Clusterin | PF01093 |
| C-type lectin (CTL) or carbohydrate-recognition domain (CRD) | CLECT | Lectin_C | PF00059 |
| Connexin homologues | CNX | Connexin | PF00029 |
| Fibrillar collagens C-terminal domain | COLFI | COLFI | PF01410 |
| Corticotropin-releasing factor | CRF | CRF | PF00473 |
| Granulocyte-macrophage colony-simulating factor (GM-CSF) | CSF2 | GM_CSF | PF01109 |
| Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein | CUB | CUB | PF00431 |
| Defensin/corticostatin family | DEFSN | Defensin_beta | PF00711 |
| Homologues of snake disintegrins | DISIN | Disintegrin | PF00200 |
| DM4/DM12 family of domains in Drosophila melanogaster proteins of unknown function | DM4_12 | DM4_12 | PF07841 |
| Cysteine-rich domain currently specific to Drosophila | DM6 | DUF1431 | PF07248 |
| Possible catecholamine-binding domain present in a variety of eukaryotic proteins | DoH | DOMON | PF03351 |
| Delta serrate ligand | DSL | DSL | PF01414 |
| Epidermal growth factor-like domain | EGF | EGF | PF00008 |
| Calcium-binding EGF-like domain | EGF_CA | EGF_CA | PF07645 |
| Laminin-type epidermal growth factor-like domain | EGF_Lam | Laminin_EGF | PF00053 |
| Endothelin | END | Endothelin | PF00322 |
| Ependymins | EPEND | Ependymin | PF00811 |
| Ephrin receptor ligand binding domain | EPH_lbd | Ephrin_lbd | PF01404 |
| Four repeated domains in the Fasciclin I family of proteins, present in many other contexts | FAS1 | Fasciclin | PF02469 |
| Fibrinogen-related domains (FReDs) | FBG | Fibrinogen_C | PF00147 |
| Fungal-type cellulose-binding domain | fCBD | CBM_1 | PF00734 |
| Fibronectin type 1 domain | FN1 | fn1 | PF00039 |
| Fibronectin type 2 domain | FN2 | fn2 | PF00040 |
| Frizzled | FRI | Fz | PF01392 |
| Furin-like repeats | FU | Furin-like | PF00757 |
| G2 nidogen domain and fibulin | G2F | G2F | PF07474 |
| Gastrin / cholecystokinin / caerulein family | GASTRIN | Gastrin | PF00918 |
| Glycoprotein hormone alpha chain homologues | GHA | Hormone_6 | PF00236 |
| Glycoprotein hormone beta chain homologues | GHB | Cys_knot | PF00007 |
| Domain containing Gla (gamma-carboxyglutamate) residues | GLA | Gla | PF00594 |
| Glucagon like hormones | GLUCA | Hormone_2 | PF00123 |
| Glycosyl hydrolase family 10 | Glyco_10 | Glyco_hydro_10 | PF00331 |
| Glyco_18 | Glyco_18 | Glyco_hydro_18 | PF00704 |
| Glycosyl hydrolases family 25 | Glyco_25 | Glyco_hydro_25 | PF01183 |
| Glycosyl hydrolases family 32 | Glyco_32 | Glyco_hydro_32 | PF00251 |
| G-protein-coupled receptor proteolytic site domain | GPS | GPS | PF01825 |
| Granulin | GRAN | Granulin | PF00396 |
| Hint (Hedgehog/Intein) domain C-terminal region | HintC | Hint | PF01079 |
| Hint (Hedgehog/Intein) domain N-terminal region | HintN | Hint | PF01079 |
| Domain present in hormone receptors | HormR | HRM | PF02793 |
| Hemopexin-like repeats | HX | Hemopexin | PF00045 |
| Hydrophobins | HYDRO | Hydrophobin | PF01185 |
| Insulin growth factor-binding protein homologues | IB | IGFBP | PF00219 |
| Interferon alpha, beta and delta | IFabd | Interferon | PF00143 |
| Interleukin-10 family | IL10 | IL10 | PF00726 |
| Interleukin-2 family | IL2 | IL2 | PF00715 |
| Interleukins 4 and 13 | IL4_13 | IL4 | PF00727 |
| Interleukin-6 homologues | IL6 | IL6 | PF00489 |
| Interleukin-7 and interleukin-9 family | IL7 | IL7 | PF01415 |
| Insulin / insulin-like growth factor / relaxin family | IlGF | Insulin | PF00049 |
| Integrin beta subunits (N-terminal portion of extracellular region) | INB | Integrin_beta | PF00362 |
| Integrin alpha (beta-propellor repeats) | Int_alpha | Integrin_alpha | PF00357 |
| Kazal type serine protease inhibitors | KAZAL | Kazal_1 | PF00050 |
| Kazal type serine protease inhibitors | KAZAL | Kazal_2 | PF07648 |
| Knottins | Knot1 | Defensin_2 | PF01097 |
| Kringle domain | KR | Kringle | PF00051 |
| BPTI/Kunitz family of serine protease inhibitors | KU | Kunitz_BPTI | PF00014 |
| Laminin B domain | LamB | Laminin_B | PF00052 |
| Laminin G domain | LamG | Laminin_G_1 | PF00054 |
| Laminin N-terminal domain (domain VI) | LamNT | Laminin_N | PF00055 |
| LCCL | LCCL | LCCL | PF03815 |
| Low-density lipoprotein receptor domain class A | LDLa | Ldl_recept_a | PF00057 |
| Leukemia inhibitory factor | LIF_OSM | LIF_OSM | PF01291 |
| Link (Hyaluronan-binding) | LINK | Xlink | PF00193 |
| Lipoprotein N-terminal Domain | LPD_N | Vitellogenin_N | PF01347 |
| Ly-6 antigen / uPA receptor -like domain | LU | UPAR_LY6 | PF00021 |
| Low-density lipoprotein-receptor YWTD domain | LY | Ldl_recept_b | PF00058 |
| Alpha-lactalbumin / lysozyme C | LYZ1 | Lys | PF00062 |
| Lysozyme subfamily 2 | LYZ2 | Glucosaminidase | PF01832 |
| Membrane-attack complex / perforin | MACPF | MACPF | PF01823 |
| Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others) | MAM | MAM | PF00629 |
| Domain involved in innate immunity and lipid metabolism | ML | E1_DerP2_DerF2 | PF02221 |
| NEAr Transporter domain | NEAT | NEAT | PF05031 |
| Nerve growth factor (NGF or beta-NGF) | NGF | NGF | PF00243 |
| Neurohypophysial hormones | NH | Hormone_5 | PF00184 |
| Extracellular domain of unknown function in nidogen (entactin) and hypothetical proteins | NIDO | NIDO | PF06119 |
| Domain found in Notch and Lin-12 | NL | Notch | PF00066 |
| Neuromedin U | NMU | NMU | PF02070 |
| Tissue inhibitor of metalloproteinase family | NTR | TIMP | PF00965 |
| DNA/RNA non-specific endonuclease* | NUC | Endonuclease_NS | PF01223 |
| Olfactomedin-like domains | OLF | OLF | PF02191 |
| Osteopontin | OSTEO | Osteopontin | PF00865 |
| Phospholipase A2 | PA2c | Phospholip_A2_1 | PF00068 |
| Pancreatic hormones / neuropeptide F / peptide YY family | PAH | Hormone_3 | PF00159 |
| Divergent subfamily of APPLE domains | PAN_AP | PAN | PF00024 |
| Bacterial periplasmic substrate-binding proteins | PBPb | SBP_bac_3 | PF00497 |
| P or trefoil or TFF domain | PD | Trefoil | PF00088 |
| Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family | PDGF | PDGF | PF00341 |
| Papain family cysteine protease | Pept_C1 | Peptidase_C1 | PF00112 |
| Insect pheromone/odorant binding protein domains | PhBP | PBP_GOBP | PF01395 |
| Repeats in polycystic kidney disease 1 (PKD1) and other proteins | PKD | PKD | PF00801 |
| Major prion protein | PRP | Prion | PF00377 |
| Paramecium Surface Antigen Repeat | PSA | Paramecium_SA | PF01508 |
| Domain found in Plexins, Semaphorins and Integrins | PSI | PSI | PF01437 |
| Plant trypsin inhibitors | PTI | Squash | PF00299 |
| Pentraxin / C-reactive protein / pentaxin family | PTX | Pentaxin | PF00354 |
| Pancreatic ribonuclease | RNAse_Pc | RnaseA | PF00074 |
| Serum amyloid A proteins | SAA | SAA | PF00277 |
| Saposin/surfactant protein-B A-type DOMAIN | SAPA | SapA | PF02199 |
| Saposin (B) Domains | SapB | SapB_1 | PF05184 |
| Saposin (B) Domains | SapB | SapB_2 | PF03489 |
| SCP / Tpx-1 / Ag5 / PR-1 / Sc7 family of extracellular domains | SCP | SCP | PF00188 |
| Intercrine alpha family (small cytokine C-X-C) (chemokine CXC) | SCY | IL8 | PF00048 |
| Domain found in sea urchin sperm protein, enterokinase, agrin | SEA | SEA | PF01390 |
| Semaphorin domain | Sema | Sema | PF01403 |
| ShK toxin domain | ShKT | ShTK | PF01549 |
| Somatomedin B -like domains | SO | Somatomedin_B | PF01033 |
| Scavenger receptor Cys-rich | SR | SRCR | PF00530 |
| Soybean trypsin inhibitor (Kunitz) family of protease inhibitors | STI | Kunitz_legume | PF00197 |
| Transforming growth factor-beta (TGF-beta) family | TGFB | TGF_beta | PF00019 |
| Thaumatin family | THN | Thaumatin | PF00314 |
| Tachykinin family | TK | Tachykinin | PF02202 |
| Tumour necrosis factor family | TNF | TNF | PF00229 |
| Tumor necrosis factor receptor / nerve growth factor receptor repeats | TNFR | TNFR_c6 | PF00020 |
| Transferrin | TR_FER | Transferrin | PF00405 |
| Transthyretin | TR_THY | Transthyretin | PF00576 |
| Trypsin-like serine protease | Tryp_SPc | Trypsin | PF00089 |
| Thrombospondin type 1 repeats | TSP1 | TSP_1 | PF00090 |
| Thyroglobulin type I repeats | TY | Thyroglobulin_1 | PF00086 |
| Uteroglobin | UTG | Uteroglobin | PF01099 |
| von Willebrand factor (vWF) type C domain | VWC | VWC | PF00093 |
| von Willebrand factor (vWF) type D domain | VWD | VWD | PF00094 |
| Four-disulfide core domains | WAP | WAP | PF00095 |
| Wnt-inhibitory factor-1 like domain | WIF | WIF | PF02019 |
| Found in Wnt-1 | WNT1 | wnt | PF00110 |
| Present in yeast cell wall integrity and stress response component proteins | WSC | WSC | PF01822 |
| Zinc-dependent metalloprotease | ZnMc | Peptidase_M10 | PF00413 |
| Zona pellucida (ZP) domain | ZP | Zona_pellucida | PF00100 |
| ADAM-TS Spacer 1 | - | ADAM_spacer1 | PF05986 |
| Animal haem peroxidase | - | An_peroxidase | PF03098 |
| Antistasin | - | Antistasin | PF02822 |
| Copper type II ascorbate-dependent monooxygenase, C-terminal domain | - | Cu2_monoox_C | PF03712 |
| Copper type II ascorbate-dependent monooxygenase, N-terminal domain | - | Cu2_monooxygen | PF01082 |
| Laminin Domain I | - | Laminin_I | PF06008 |
| Laminin Domain II | - | Laminin_II | PF06009 |
| Laminin G domain | TSPN | Laminin_G_2 | PF02210 |
| Class I Histocompatibility antigen, domains alpha 1 and 2 | - | MHC_I | PF00129 |
| Class II histocompatibility antigen, beta domain | - | MHC_II_beta | PF00969 |
| Agrin NtA domain | - | NtA | PF03146 |
| Reprolysin (M12B) family zinc metalloprotease | - | Reprolysin | PF01421 |